Background There is ongoing debate regarding whether and under which circumstances secondary findings (SF) should be offered in the pediatric context. Although studies have examined patient perspectives on receiving SF, little research has been conducted examining the experiences of clinicians offering SF to parents of newborns receiving genomic sequencing for a recently diagnosed medical condition.Methods To address this, we conducted qualitative interviews exploring the views and experiences of 12 clinicians who offered SF to parents of infants who had diagnostic exome (...) sequencing (ES) to identify the cause of their hearing loss. Interviews explored clinicians’ accounts of parents’ choices and decision-making about receiving SF, their views on whether and when to offer SF, their experiences returning SF, and any ethical challenges they encountered. Interviews were audio-recorded, transcribed and analyzed using inductive content analysis.Results Clinicians reported parents who declined all SF often felt finding out about future conditions unrelated to their child’s hearing loss may be unhelpful, or even harmful, or were overwhelmed by their child’s diagnosis. Clinicians also reported that some parents chose SF because they felt obliged to, even if they did not want to receive them. They explained that while some parents experienced decision-making regarding SF as positive, for others, this process was challenging or distressing. While clinicians generally agreed SF should be offered, mainly to promote parental choice, most felt SF should be offered after disclosing diagnostic results, primarily to avoid overwhelming parents. Clinicians encountered several ethical challenges, including balancing parental autonomy with non-maleficence, wanting to report or not report certain SF, and questioning whether parents can make an autonomous choice regarding SF.Conclusions Our findings, which are novel as they relate to parents of young infants with a recent diagnosis of hearing loss, add new insights into clinicians’ and parents’ decision-making regarding SF in pediatrics. (shrink)

Growing evidence suggests that natural environments – whether in outdoor or indoor settings – foster psychological health and physiological relaxation, indicated by increased wellbeing, reduced stress levels, and increased parasympathetic activity. Greater insight into differential psychological aspects modulating psychophysiological responses to nature-based relaxation videos could help understand modes of action and develop personalized relaxation interventions. We investigated heart rate variability as an indicator of autonomic regulation, specifically parasympathetic activity, in response to a 10-min video intervention in two consecutive studies as (...) well as heart rate. We hypothesized that a nature-based relaxation video elicits HRV increase and HR decrease, with response magnitude being affected by aspects of early life adversity and trait mindfulness. In Study 1, N = 60 participants watched a relaxation video intervention depicting different natural scenery. We analyzed changes in HR and respiratory sinus arrhythmia as a standard HRV measure, both based on 3-min segments from the experimental session, in multiple growth curve models. We found a decrease in HR and increase of RSA during the video intervention. Higher paternal care and lower trait mindfulness observing skills were associated with higher RSA values before but not during video exposure. In Study 2, N = 90 participants were assigned to three video conditions: natural scenery from Study 1, meditation video, or short clip from “The Lord of the Rings.” Again, HR decreased, and RSA increased during video segments, yet without expected group differences across different video types. We found higher parental care and lower parental overprotection to predict higher RSA at different times during the experiment. Interestingly, lower paternal overprotection predicted overall higher RSA. These results suggest a generic relaxation effect of video interventions on autonomic regulation that we discuss in light of different theories mapping restorative effects of natural environments. Further, psychological characteristics like aspects of early life adversity and trait mindfulness could contribute to individual differences in autonomic regulation. This study contributes to a better understanding of autonomic and psychological responses to relaxation videos. (shrink)

Part novella, part philosophy, Clara was Schelling's most popular work during his lifetime, and appears here in English for the first time.

To this day, the Italian Jewish literary postwar canon is undisputedly ruled by Primo Levi, Giorgio Bassani and Carlo Levi. This study of three major Italian Jewish women writers – Natalia Ginzburg, Clara Sereni and Lia Levi – highlights the presence in Italian literature of a subversive Jewish écriture feminine. These writers’ formal independence and subversive redeployment of narrative and thematic strategies not only consolidated a strong female voice in Italian literature but also produced a specific Italian brand of (...) Jewish literature. The following analysis shows how, through their literary ‘life miniatures’, Ginzburg, Sereni and Levi recentre the domestic everydayness of woman’s personal and historical experience, while, simultaneously, challenging the traditional representations of women’s positions within family and within the public space, as well as interrogating their Jewish identity vis-a-vis their country’s Fascist past. In particular, this article focuses on the way in which all three authors portray themselves as women trying to strike a balance between their Jewish identity and history alive only in the domestic space of their family lives, and their gender identity which is repressed by the patriarchal system both in the house and in the public arena. These women respond by moving ‘out’ of their homes, by exploring the city space – thus turning the ‘urban monster’ into a positive locus for women’s self-determination and political action – and by bonding with other women. Through a demasculinization of the city space, these memoirs re-elaborated notions of family, Judaism, private and historical memory, and they reinvented a poetics for the ‘small virtues’ of woman’s everyday existence while also pioneering a new space in literature that radically changed the direction of patriarchal Italian culture in the second half of the twentieth century. (shrink)

The article presents a critical evaluation on the concept of justice as equality proposed by John Rawls. Based on the analysis of the latest book written by Rawls the article defends (1) the necessary compromise in any kind of political concept interested in the justice with real and individual f..

Si le nom d’Albert Camus continue de s’imposer, aujourd’hui, comme une figure incontournable de la littérature et de la pensée françaises du XXe siècle, il n’en est pas moins demeuré une personnalité cosmopolite, sensible à ce que la culture ne s’accomplit véritablement qu’en l’absence de sectarisme, qu’en présence de l’autre — avec ou envers lui, peu importe. C’est aussi tout le sens de la collection « Exotopies » de l’Association portugaise des études françaises (A.P.E.F.) qu’inaugure ce volume : présenter des (...) travaux sur la langue et la culture françaises, mais d’un point de vue singulier, celui d’un autre pays. En lisant ce bouquet assez restreint, mais en même temps assez diversifié de travaux sur l’oeuvre d’Albert Camus, on relèvera donc qu’il ne s’agissait ni d’un hommage, ni d’une commémoration, si contraires au vif esprit de la littérature, mais de s’aviser de l’exceptionnelle variété et actualité de son oeuvre. En ce sens, il n’est de meilleure figure pour débuter cette collection à visée cosmopolite que celle d’Albert Camus, chez qui le geste d’écriture est totalement inscrit dans une vocation humaniste. Celle-ci ne s’entend pas dans un sens moraliste, mais dans un sens existentiel — sinon existentialiste —, qui veut que chacun se définisse par le souci qu’il a de l’autre, et que l’humanité s’apparaisse comme le perpetuum mobile de l’histoire, en même temps que son point fixe, son sens dernier. (shrink)

Reseña Ruvituso, Clara. Diálogos existenciales. La filosofía alemana en la Argentina peronista (1946-1955). Madrid, Iberoamerica-Vervuert, 2015, 368 pp.

La psicología contemporánea parece caracterizarse desde sus propios orígenes por la multiplicidad de sus contenidos, además de por su casi infinita fragmentación en corrientes encontradas. Esto crea importantes dificultades, no sólo a quienes quieran tener una primera aproximación, sino también a los especialistas, que muchas veces no llegan a una opinión suficientemente clara sobre la naturaleza epistemológica de la psicología, ni sobre su unidad disciplinar. Esta obra, sin descuidar el problema global, se centra en un aspecto particular: el que (...) presenta la praxis de la psicología, en particular la psicoterapia y sus fundamentos teóricos. Se pone especial interés en una visión crítica del psicoanálisis, punto de referencia inevitable (positivo o negativo) para la mayoría de las corrientes de psicoterapia. Pero este intento de esclarecimiento epistemológico y práctico se lleva a cabo desde un punto de vista original: a la luz del pensamiento de Santo Tomás de Aquino (1225-1274), conocido como uno de los más grandes teólogos y filósofos de la Iglesia Católica. Las calidades del Aquinate como epistemológico son sobradamente conocidas. Menos conocida es su faceta de psicólogo, que esta obra quiere poner de manifiesto con gran detalle para evidenciar la actualidad de las líneas maestras de la psicología de Santo Tomás, como también la posibilidad de practicar hoy la psicología bajo la guía fundamental del Doctor Humanitatis.\n. (shrink)

Developing and applying a framework for understanding the complexities of economic and legal considerations in two recent Supreme Court rulings was the focus of this research. Of especial concern was the protection of intellectual property in the pharmaceutical industry. Two cases from 2013 were selected: FTC v. Activis and Association for Molecular Pathology v. Myriad Genetics, Inc.. Part of the rationale for the selection was the importance of the Supreme Court rulings and the importance of the pharmaceutical sector. A qualitative (...) content analysis of the Court’s reported decision in each case was analyzed. Since ethical considerations may or may not be consistent with efficiency considerations of plaintiffs, defendants, or the courts, both efficiency and ethical arguments were included. Equally important to the understanding of the economic and ethical issues in the two above- mentioned cases was the development of a rationale for including and excluding a variety of ethical theories, ultimately influenced by Markkula Center For Applied Ethics Of Santa Clara University and Schumann :93–111, 2001). The refinement and use of a levels analysis approach portrays societal, organizational, and individual impacts, and allows for deeper understanding of litigated cases, irrespective of the country in which the litigation takes place :385–393, 2004; Foss et al., J Manag Stud 47:455–482, 2010). A rationale for this framework is the societal and organizational impacts on the myriad of stakeholders in the pharmaceutical sector. We suggest that this framework can be applied to other industries and other complex conflicts among stakeholders as well. (shrink)

El propósito de este artículo es el de justificar una interpretación genuinamente hegeliana de la dimensión religiosa en el pensamiento de Hegel, particularmente a partir de la Fenomenología del espíritu. Tanto la izquierda como la derecha hegeliana desarrollaron un carácter unívoco, o bien reduciendo el concepto hegeliano de lo divino a la razón natural o histórica, o bien pasando por alto que la concepción hegeliana de una divinidad inmanente resultaba incompatible con el cristianismo ortodoxo. Analizaremos en detalle los capítulos de (...) la Fenomenología del espíritu que se centran en la Ilustración, en los cuales el autor se desmarca de forma más clara de lo que podría ser una religiosidad puramente deísta. Finalmente, la propuesta de Hegel consistirá en un modelo orgánico de estado, dentro del cual la religión sería aceptada como parte de la misma substancia ética que fundamenta las leyes de cada comunidad. (shrink)

Western societies today are coming unmoored in the face of an earth-shaking ethical and cultural paradigm shift. At its core is the question of what it means to be human and how we are meant to live. The old answers are no longer accepted; a dizzying array of options are offered in their stead. Underpinning this smorgasbord of lifestyles is a thicket of unquestioned assumptions, such as the separation of gender from biological sex, which not so long ago would have (...) been universally rejected as radical notions. In the spring of 2019, a group of Orthodox Christian scholars drawn from a wide variety of academic disciplines met together to offer responses to the moral crisis our generation faces, elaborating upon its various forms and facilitating a fuller understanding of some of its theological and philosophical foundations. In doing so they offer support to all those who question the claims that are so forcefully insisted upon today--a clarity that will aid them in standing up and resisting trends that have already shown to be the cause of great suffering and unhappiness. (shrink)

(There are occasional changes to the text. "F" refers to A. Friedberg, Corpus iuris canonici, Leipzig, 1879. "S" refers to Seraphicae legislationis textus originales iussu Rmi Patris Ministri Generalis totius Ordinis Fratrum Minorum in lucem editi (Ad Claras Aquas, 1897).).

Foundations of Dialectical Psychology is a compilation of the writings of Klaus F. Riegel on dialectical psychology. The book presents chapters discussing such topics as the dialectics of human development; history of dialectical psychology; temporal organization of dialogues; and the analysis of the concept of crisis and its underlying philosophical model and ideology. Psychologists and students will find the book invaluable.

This article explores some of the ways in which the conceptual apparatus of A Thousand Plateaus, and especially its machinic metaphysics, can be connected to recent developments in computer modelling and social simulation, which provide new tools for thinking that are becoming increasingly popular among philosophers and social scientists. Conversely, the successful deployment of these tools provides warrant for the flat ontology articulated in A Thousand Plateaus and therefore contributes to the ‘reversal of Platonism’ for which Deleuze had called in (...) his earlier works, such as Logic of Sense. The first major section offers a brief exposition of some key concepts in A Thousand Plateaus in order to set the stage for the second and third major sections, which argue that the fabrication of a metaphysics of immanence can be accelerated by connecting its conceptual apparatus more explicitly to insights derived from philosophical analyses of computational modelling and simulation and the social scientific use of ‘assemblage theory’. The article concludes with a summary of the argument and a brief consideration of some of the potential ethical and political implications of this interdisciplinary engagement. (shrink)